Dr Castellano is a nationally recognized speaker having presented well over 100 lectures in the field of reconstructive surgery for the foot and ankle. He graduated from Georgia Southern University in 1982. In 1986, he received his doctorate degree from the Pennsylvania College of Podiatric Medicine in Philadelphia. Dr. Castellano completed his surgical training at Northlake Regional Medical Center in Atlanta, Georgia. He began his practice in Fort Myers and Bonita Springs in 1989. He is Board Certified by the American Board of Podiatric Surgery.

In 1991, and again, in 1993 Dr Castellano spent a month in Perth, Australia performing complex surgical procedures on several children and adults. Most of the podiatrists in Perth spent the month observing and improving their surgical skills under Dr. Castellano's supervision.

Dr. Castellano is an avid saltwater flyfisherman and enjoys his sport in the waters around Sanibel Island.